Our findings provide direct evidence that memory repression in dissociative amnesia is associated with an altered pattern of neural activity, and they suggest the possibility that the pFC has an important role in inhibiting the activity of the hippocampus in memory repression. After treatment for retrograde amnesia, the altered pattern of brain activation disappeared in one patient whose retrograde memories were recovered, whereas it remained unchanged in the other patient whose retrograde memories were not recovered. In the comparison of the unrecognizable condition with the recognizable condition, we found increased activity in the pFC and decreased activity in the hippocampus in both patients. During fMRI, the patients were visually presented with these stimuli and asked to indicate whether they were personally acquainted with them. The disorder is commonly accompanied by other symptoms and behaviors, such as fatigue, insomnia, depression, suicidal behavior, and substance abuse. For each patient, three categories of face photographs and three categories of people's names corresponding to the photographs were prepared: those of “recognizable” high school friends who were acquainted with and recognizable to the patients, those of “unrecognizable” colleagues who were actually acquainted with but unrecognizable to the patients due to their memory impairments, and “control” distracters who were unacquainted with the patients. Dissociative amnesia is a mental health disorder in which a person cannot remember information about their lifeoften as a result of experiencing some form of trauma or stress. We used fMRI to investigate neural activity associated with memory retrieval in two patients with dissociative amnesia. A person with amnesia may not be aware of memory losses or may experience significant distress. The memory loss is rarely complete and more commonly includes specific time periods, events, or people. However, the neural mechanisms underlying this condition are not clear. Dissociative amnesia is a mental illness that is characterized by unusual memory loss related to a traumatic experience. It is thought to reflect a reversible deficit in memory retrieval probably due to memory repression. What is it like to have dissociative amnesia Everyone’s experience with dissociative amnesia is different. Amnesia is a memory disorder attributed to infections, brain diseases, or other medical conditions.
Dissociative amnesia usually follows a stressful event and cannot be attributable to explicit brain damage. Dissociative amnesia is characterized by the inability to important personal information, usually following an extremely stressful or traumatic experience and. Dissociative amnesia is a dissociative disorder often resulting from a traumatic or severely stressful event.
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